Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth
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چکیده
منابع مشابه
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The tumor suppressor p53 can trigger cell death independently of its transcriptional activity through subcellular translocation and activation of proapoptotic Bcl-2 family members. The regulation of such activity of endogenous p53 in response to stress remains largely unknown. Here we show that nuclear, activated FOXO3a could impair p53 transcriptional activity. However, activation of FOXO3a ei...
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ژورنال
عنوان ژورنال: PLOS Biology
سال: 2018
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.2002912